You smartly recall the diagnostic criteria for DKA and realise you just need the third part:
- Ketonaemia > 3.0mmol/L or significant ketonuria (more than 2+ on standard urine sticks)
- Blood glucose > 11.0mmol/L or known diabetes mellitus
- Bicarbonate (HCO3- ) < 15.0mmol/L and/or venous pH < 7.3
You also remember that the difference between venous and arterial pH is 0.02-0.15 pH units. No one cares about that in DKA, so you spare the patient the agony of an ABG. The analyser reads:
pH 7.01
pCO2 2.9 kPa
pO2 7.6 kPa
HCO3 7 mmol/L
Base Excess -11 mEq/L
Lactate 3.0 mmol/L
Na 131 mmol/L
K 4.1 mmol/L
Glucose 17.2 mmol/L
The patient’s observations are:
Pulse 111, BP 112/66 mmHg, Temp 37.1, RR 24, Sats 100% oa
What is the next step of management?
Normal saline 0.9% @ 1 Litre / 1 hour
Normal saline 0.9% with 40 mmol KCl @ 1 Litre / 1 hour
Soluble insulin (Actrapid® or Humulin S®) @ 0.1 units/Kg/hr